According to the order of operations, we should perform any powers before multiplications. Thus, we begin by simplifying \((2xy^2)^4\text{.}\) We apply the fourth law.
\begin{align*}
5x^2 y^3\left(2xy^2\right)^4 \amp = 5x^2 y^3 \cdot 2^4x^4\left(y^2\right)^4 \amp\amp\blert{\text{Apply the fourth law.}}\\
\amp = 5x^2 y^3 \cdot 2^4x^4 y^8
\end{align*}
Finally, multiply powers with the same base. Apply the first law.
\begin{equation*}
5x^2 y^3 \cdot 2^4x^4 y^8 = 5 \cdot 2^4 x^2x^4 y^3 y^8 = 80x^6 y^{11}
\end{equation*}